Senior Quality Scientist IThis position will contribute to Addgene's mission to accelerate research and discovery by improving access to useful research materials and information through ensuring only the highest quality materials are distributed to scientists. The Senior Quality Scientist I will help the Quality team grow Addgene's catalogue of items available for customers to order while sustaining our high quality of materials offered. Additionally, this position will grow the team's computational and quality analysis capabilities.Position Reported ToSr. Manager, QualityApproximate Start DateASAPSalary$84,000 - 92,000 annually + our amazing benefits! (see below)Location & Policy on Remote WorkThis is a hybrid position, with Wednesdays required onsite in our Watertown, Massachusetts Headquarters. Our beautiful office space has free, ample parking with a complimentary shuttle from Harvard Square and is on multiple bus lines, with the cost of public transit covered by Addgene for those onsite at least twice a week.ResponsibilitiesIn this position, you will support Addgene's mission to deliver only the highest quality materials to scientists around the world. The Senior Quality Scientist I independently owns complex QC analyses and depositor relationships, leads new process development within the QC team, and contributes bioinformatic and scripting expertise to team capability expansion. This role is expected to proactively identify gaps and opportunities within the QC team's existing scope, propose projects, and execute them with minimal direction.Independently perform, document, and report quality control (QC) analysis across all sample types and complexity levels, including resolving novel or non-routine QC issues.QC analysis includes verifying sample functionality through DNA sequence analysis of Illumina and Nanopore next generation sequencing data, as well as diagnostic restriction enzyme digests.Serve as escalation point for complex depositor communications before escalation up; own end-to-end resolution of difficult casesProvide bioinformatic, script writing, and command line expertise to new project development and process optimization plansLead NGS-related bioinformatic processes; serve as a technical resource for post-run data processing, pipeline management, uploading of sequencing results, and troubleshooting.Perform additional Quality team duties for specialized sample analyses, internal team processes, and external team communications.Contribute to the development of Quality Control team goals and best practices; lead discussions on progress and alignment at team meetingsServe as a subject and technical expert on QC tasks, answer team questions, cross-train team members, and update and improve team processes and SOPs.Develop and lead new team initiatives to improve quality, efficiency, and scope of performing QC analyses on a variety of samples through different means.Author, update, and maintain new SOPs for developmental processes. Cross-train team members on new processes upon launch.Occasionally contribute to outreach/marketing initiatives and/or to educational content on our website.Skills and CompetenciesPhD in Biological Sciences or other life science, MS with 4+ years related experience, or equivalent combination of education and experience.Experience with cloning, primer design, and sequence analysis requiredExperience with a programming or scripting language (Python, Bash, R, etc) and command line toolsExperience with next-generation sequencing analysis using bioinformatic software requiredWorking knowledge of standard molecular biology practices including bacterial transformations, DNA preparation, and digestsWell versed in reading scientific research articlesExcellent organizational skills and attention to detailAble to manage multiple tasks efficientlySelf-motivated, proactive with desire for continuous improvementMentoring mindset, demonstrating patience and clarity in explanationsStrong leadership skills with ability to communicate complex information succinctlyAbility to adapt to changing lab priorities, new technologies, or unforeseen challenges, finding innovative ways to manage them.Ability to write technical reports and document outcomes of projectsAbility to work independently and as a member of a cross functional teamMust be able to communicate effectively in English; strong written, verbal, and interpersonal communication skills and ability to work closely with scientists requiredFamiliarity with general computer software, including sequence analysis software, Google Workspace, and MS OfficeBenefitsAt Addgene, we prioritize our people with comprehensive benefits that support both your work and your life.85% company-paid healthcare premiums including dental (extending to family members) and 100% company-paid deductibleLife, short-term, and long-term disability insurance.22 days of PTO on top of our winter break closure and company holidays.A 403(b) retirement account with a company match of 4% after 2 years of employment.Annual professional development stipendAnnual lifestyle stipendFully paid public transportation for employees who work onsite four or more days per week.Onsite yoga classes & wellness reimbursementPet insuranceAnnual financial planning one-on-ones with our plan administratorEqual Opportunity EmployerAddgene is an Equal Opportunity Employer and considers all applicants without regard to race, color, religion, national origin, sex, ancestry, sexual orientation, genetic information, gender identity, active military or veteran status, age, handicap, or any other characteristic protected by Federal, State or Local law.#J-18808-Ljbffr